Protein C Immunodepleted Deficient Human Plasma
| 6-FDPPC-10 | Kit | 10 x 1.0 mL |
| 6-FDPPC | Bottle | 1 x 100 mL |
Immunodepleted deficient plasma for protein C assay
Description of the Protein C Immunodepleted Deficient Human Plasma
Pooled normal citrated human plasma depleted of protein C using antibodies directed
to protein C immobilized on agarose beads. Plasma contains 20 mM Hepes.
Advantages
- No bovine additives
- No reconstitution error
- No deterioration of plasmas linked to freeze-drying
- Cryotubes ready to use after thawing (4 min at 37°C).
Informations
Protein C is a 62 kDa glycoprotein, synthesized by the liver in the presence of vitamin K. CP is at the center of a physiological system that inhibits coagulation: the anticoagulant system of protein C. Thrombin associated with thrombomodulin loses its procoagulant properties at the same time as it activates PC to active protein C (PCa).
PCa in the presence of protein S, calcium and phospholipids is capable of cleaving FVa and FVIIIa blocking the amplification loop of thrombin generation.
