PAI-1 Immunodepleted Deficient Human Plasma  

 

Immunodepleted deficient plasma for PAI-1 assay.

Plasminogen activator inhibitor 1 (PAI-1) immunodepleted human plasma buffered with 20mM HEPES.


Advantages

- No bovine additives
- No reconstitution error
- No deterioration of plasmas linked to freeze-drying
- Cryotubes ready to use after thawing (4 min at 37°C).


Informations

Plasminogen activator inhibitor (PAI-1) is a glycoprotein, the main inhibitor of t-PA and u-PA. It plays an important role in controlling excessive fibrinolysis. PAI-1 is mainly synthesized by vascular endothelial cells, as well as by other cells (hepatocyte, SMC, fibroblasts...). It circulates in plasma in 3 forms: an active form bound to vitronectin, a latent free form and an inactive form. By inhibiting t-PA and u-PA, PAI-1 limits plasminogen activation and controls fibrinous thrombus degradation.


Documentation

Download the product sheet
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Fresh Frozen Plasmas
 
 
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References

6-FDPPAIBottle1 x 100 mL
6-FDPPAI-10Kit10 x 1.0 mL