Plasma with Factor V Leiden (homozygous mutation)

 

Advantages

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Ready to use.


Informations

The Leiden mutation on factor V induces resistance to active Protein C.
This mutation leads to the replacement at position 506 of an arginine by a glutamine, which affects the site of cleavage of factor V by PCa.
Factor V then loses its role as a cofactor of the C protein system, a coagulation inhibitor system.
Factor V retains its procoagulant properties.


Documentation

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References

6-PPMFVLHOVial1 x 1.0 mL