The Leiden mutation on factor V induces resistance to active Protein C.
This mutation leads to the replacement at position 506 of an arginine by a glutamine, which affects the site of cleavage of factor V by PCa.
Factor V then loses its role as a cofactor of the C protein system, a coagulation inhibitor system.
Factor V retains its procoagulant properties.
Special plasmas are derived from patients with a congenital deficiency, severe or moderate, or presenting a particular profile.
No buffer or preservatives are added. Quickly frozen at -80° C, the plasma maintains perfectly intact the matrix.
All plasmas are stable when stored at -40° C to -80° C.
We carefully pack with dry ice during shipment.
No additive or preservative.
Expiry date > 1 year.
Plastic vials.
Minimize test time.
Ready to use.
