Human Beta-thrombin

Optimize your coagulation studies, cell signaling, or enzyme-substrate interactions with our highly purified human β-thrombin and γ-thrombin enzymes. Derived from controlled digestion of α-thrombin, these isoforms retain their 3D structure while exhibiting a coagulant activity of <1%—ideal for experimental models where active coagulation is not desired.

🔬 Purity > 95% | 🔒 Thrombin Activity < 1% | 🧪 Formats 100 µg & 1 mg | ❄️ Stability 12 months at -80/-40°C, protected from light and moisture

Properties:

• Chemical Formula: Human protein derived from α-thrombin

• Purity: >95% (SDS-PAGE assessment)

• Coagulant Activity: <1% relative to active α-thrombin

• Molecular Weight: Approximately 34 kDa

• Formulation: Phosphate buffer solution Na3PO4 10 mM, pH ~6.5, 0.1% PEG 8000

• Packaging: 100 µg or 1 mg lyophilized

• Recommended Storage: -80/-40°C, protected from light and moisture

• Shelf Life: 12 months under recommended storage conditions

Certified High Purity with Strict Quality Control
Very low coagulant activity, minimizing adverse effects in your assays

Stabilized formulation in phosphate buffer with PEG for optimal preservation

Fast delivery and guaranteed traceability with Technical Data Sheets (TDS) and Safety Data Sheets (SDS) provided

Suitable for academic and industrial research, biotechnology, and biopharmaceutical development

Bulk delivery available

All references benefit from volume-based pricing.

An enzyme is a protein that catalyzes a biochemical reaction. It converts a substrate into a product. Each enzyme has a structure tailored to its function, and its activity depends on an optimal temperature and pH. Beta-thrombin is obtained by cleavage of alpha-thrombin at the intact B chain at the Arg106-Tyr107 bond to produce the B1 and B2 fragments.