Detection and determination of proteinases, studies on their interactions with substrates and effectors and the investigation of their physiological role are greatly facilitated by the use of proteinase inhibitors. In this context, especially synthetic, low-molecular weight inhibitors of different selectivity are very useful. They are widely applied during purification and characterization of proteinases. Furthermore, synthetic inhibitors are useful tools for suppression of undesired proteolytic activity. Depending upon the manner in which the inhibitor is attached to the enzyme, one distinguishes reversible and irreversible inhibitors. Biotinylation allows the peptides to be used as specific probes for the detection and / or capture of serine protease via an avidin / biotin interaction.
Most inhibitors exhibit a selective inhibitory activity on certain trypsin-like proteinases of physiological relevance. However, each inhibitor will of course display a characteristic action on others serines proteinases.
Supplied lyophilized or frozen. Expiry date > 1 year. Glass vial or plastic tubes. Discount according to quantities.
