HEMOSTASIS COAGULATION RESEARCH REAGENTS INHIBITORS SYNTHETIC IRREVERSIBLE INHIBITORS
Biotinylated FPR chloromethylketone
Formulation : 10 mM HCl
MW(Da) : 940 BFPRck: Biotinylated phe-Pro-Arg-chloromethylketone which rapidly inhibits thrombin. They are often used during protein purification to inhibit serine protease activity and prevent the conversion of zymogens to active proteins.
Advantages
Supplied lyophilized or frozen. Expiry date > 1 year. Glass vial or plastic tubes. Discount according to quantities.
Informations
Detection and determination of proteinases, studies on their interactions with substrates and effectors and the investigation of their physiological role are greatly facilitated by the use of proteinase inhibitors. In this context, especially synthetic, low-molecular weight inhibitors of different selectivity are very useful. They are widely applied during purification and characterization of proteinases. Furthermore, synthetic inhibitors are useful tools for suppression of undesired proteolytic activity. Depending upon the manner in which the inhibitor is attached to the enzyme, one distinguishes reversible and irreversible inhibitors. Biotinylation allows the peptides to be used as specific probes for the detection and / or capture of serine protease via an avidin / biotin interaction.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
| 9-BFPRCK-06 | Vial | 1 mg |
