Fibrinogen is a soluble protein synthesized by the liver with a size of 340 kDa and circulating at a concentration of 2.6 to 3 mg / mL. It is a dimer linked by disulfide bonds composed of 3 pairs of non-identical polypeptide chains. Under the action of thrombin, fibrinogen is converted into fibrin. In association with FXIII, calcium ions, fibrin forms a stable network which ensures coagulation.
All proteins are accompanied by certificates of analysis which describe the appropriate storage conditions. In order for us to guarantee the stability of the product, it is imperative that the storage conditions are observed. Brief centrifugation of the zymogens in their original packaging will fully recover the sample at the bottom of the tube. Never allow protein solutions to stay at room temperature for excessive periods of time. High temperatures can increase the rate of protein degradation. Avoid storing or maintaining diluted protein samples for an extended period of time. In general, purified proteins are inherently more stable in concentrated form. Many proteins are "clingy" by nature. To avoid protein loss due to adsorption, extremely diluted protein samples should be prepared in buffers containing excipients such as bovine serum albumin, polyethylene glycol, Prionex or gelatin.
The vast majority of plasma derivatives is pure (without additives) with > 95 % purity SDS-PAGE. Expiration date of one year from delivery. Delivery in large quantities. Discount according to quantities.