HEMOSTASIS COAGULATION RESEARCH REAGENTS MONOCLONAL ANTIBODIES ANTI-PROTHROMBIN
Mouse monoclonal antibody anti-human prothrombin, IgG2a
Antigen recognized : Human prothrombin, prethrombin-1, fragment 1.2, meizothrombin and human prothrombin
Application : Immunoblotting, ELISA, inhibits clotting and prothrombin activation.
Host : Mouse
Immunogen : Human prothrombin purified
Advantages
Custom needs by supplying you conjugated with biotin, HRP, FITC or other conjugates.
Special formulations are available upon request.
Discount according to quantities
Informations
Factor II (FII) or prothrombin is a glycoprotein synthesized by the liver, zymogen of a serine protease. It is a vitamin K-dependent clotting factor. Its half-life is 50 to 120 hours. FII is activated by the prothrombinase thrombin complex which plays a central role in the coagulation process. It will transform fibrinogen into fibrin, amplify its own formation and activate the protein C, TAFI and platelet systems. There are constitutional deficits in FII which are very rare and acquired deficits which can be observed during anti-vitamin K treatments or vitamin K deficiency, CIVD, anti-FII autoantibodies.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
9-AHP-5013 | Vial | 100 µg |