HEMOSTASIS COAGULATION RESEARCH REAGENTS ENZYMES FACTOR XA
Human Factor Xa – blocked active site (BEGRck)
Structure: 2 PM subunits: 16 200 and 28 800 Da, N-terminal Gla domain and 2 EGF domains.
Formulation : 20 mM Hepes, 150 mM NaCl, pH 7.4
< 1 % FXa activity - Active-site blocked.
MW(Da) : 46 000
Extinction coef. : 11.6
Activity determined by coagulation and chromogenic tests
Advantages
The vast majority of enzymes is pure (without additives) with > 95% purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities
Discount according to quantities.
Informations
An enzyme is a protein that catalyzes a biochemical reaction. It converts a substrate into a product.
Each enzyme has a structure adapted to its function and its activity is dependent on an optimum temperature and pH.
Factor X (FX) is a glycoprotein synthesized by the liver, dependent on vitamin K. FX is involved in the common pathway of coagulation.
It is activated in FXa by the FT-FVIIa complex or by the FVIIIa-FIXa complex in the presence of phospholipids.
FXa is neutralized by TFPI and antithrombin.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
References
9-HCXA-BEGR | Vial | 100 µg |
9-HCXA-BEGR-1 | Vial | 1 mg |