The product is a murine lgG 2bK monoclonal antibody purified from mouse ascites fluid via Protein G affinity chromatography. A synthesized eight-
branched immunogenic complex was used as the immunizing antigen

This product is directed against γ-carboxyglutamyl(Gla) residues found in various coagulation proteins of human and other species and venoms. lt reacts with the Gla domains found in human prothrombin, prothrombin fragment 1, factor VII, recombinant factor VIIa, factor IX, factor X, Protein C, Protein S and bovine bone Gla protein. Ca2+ (5 mM concentration) strongly inhibits the binding of this product to human prothrombin in a non-competitive immunofluorescence assay