r-Hirudin

Formula : C₂₈₇H₄₄₀N₈₀O₁₁₀S₆
Molecular weight: 6 963.5 g/mol

Supplied lyophilized or frozen.
Expiry date > 1 year.
Glass vial or plastic tubes.
Discount according to quantities.

Hirudin is the most potent and specific thrombin inhibitor known. It forms a stable equimolar complex with thrombin. The complete structure of hirudin has been elucidated [Dodt et al., 1984] and a gene coding for hirudin was subsequently synthesized and expressed in yeast [Meyhack et al., 1987].
r-Hirudin amino acid sequence corresponds to natural hirudin of the variant HV-I except for tyrosine 63 which lacks the sulphate group.