» pNAPEP-8111

HEMOSTASIS COAGULATION RESEARCH CHROMOGENIC SUBSTRATES CHROMOGENIC SUBSTRATE FOR ACTIVATED FACTOR XII (FXIIA)

pNAPEP-8111

FXIIa chromogenic substrate

Specific synthetic chromogenic substrate for the measurement of the FXIIa activity in plasma : equivalent of Pefachrome® FXIIa/TH5253.
The chromogenic peptides are also used in quality control of pharmaceutical and other preparations.
As we are manufacturer, we can supply you from milligram to gram.

Peptide sequence : H-D-CHA-Gly-Arg-pNA, 2AcOH
Molecular Weight (+2AcOH) : 740.7 g/mol
pNA free ≤ 0.5 %
Purity grade ≥ 95 %

Reference	61038111
Presentation	Vial
Format	1 x 25 mg
M.S.D.S
Stress
Insert (s)
Quote

Reference	Presentation	Format	Quote	Product sheet
61038111	Vial	1 x 25 mg

Reference	M.S.D.S	Stress	Insert (s)
61038111

Over 20 years of expertise as manufacturer of the pNAPEP® line of chromogenic peptide substrates.
This is a line of high quality substrates, which allow testing of serine proteinases.
Their focus is on enzymes involved in coagulation and fibrinolysis for thrombin, Factor Xa, Factor XIIa, kallikrein, activated protein C, plasmin and plasminogen-SK.
Our chromogenic substrates pNAPEP are equivalent to the brand name CHROMOGENIX, WERFEN, PENTAPHARM DSM or DIAGNOSTICA STAGO.
These are synthetic peptides that react with proteolytic enzymes under formation of colour which can be followed spectrophotometrically and the intensity of which is proportional to the proteolytic activity of the enzyme.

Typically, such chromogenic substrates are composed of 3 to 5 natural or artificial amino acids. They may be N-terminally protected to reduce undesired degradation by aminopeptidases.
On their C-termini they are modified so that upon cleavage of the amide bond a chromogenic group is released. Most commonly used groups are the p-nitroaniline (pNA) which absorbs light of the wavelength of 405 nm.
Stability after reconstitution > 1 year (3 years from date of manufacture)
The substrates, after reconstitution with distilled water, are stable for 3 to 6 months between 2°C and 8°C.

Package Inserts, certificate of analysis supplied.
Material safety Data Sheet (MSDS) supplied.
Prolonged stability following reconstitution (> 3 months).
Discount according to quantities.

	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION RESEARCH CHROMOGENIC SUBSTRATES CHROMOGENIC SUBSTRATE FOR ACTIVATED FACTOR XII (FXIIA)

pNAPEP-8111

FXIIa chromogenic substrate

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HEMOSTASIS COAGULATION RESEARCH CHROMOGENIC SUBSTRATES CHROMOGENIC SUBSTRATE FOR ACTIVATED FACTOR XII (FXIIA)

pNAPEP-8111

FXIIa chromogenic substrate

Product sheet