Factor IX Inhibitor Plasma Negative Control
| 6-1950-05 | Vial | 25 x 0.5 mL |
Factor IX deficient plasmas without Factor IX inhibitor.
This plasma can be used for the negative control of the determination of Factor IX (FIX) inhibitor according to the Bethesda assays or modified Nijmegen Bethesda assays.
Description of the Factor IX Inhibitor Plasma Negative Control
Factor IX Inhibitor Plasma Negative Control is made from a pool of Factor IX deficient (<1%) human plasma.
It does not contain any specific natural inhibitor directed against the activity of Factor IX (FIX).
Informations
Treatment for hemophilia B involves injecting the missing Factor IX I.V. to prevent or stop bleeding.
A majority of the complications of this treatment are the development of antibodies against FIX, called inhibitors.
The development of an anti-FIX inhibitor leads to episodes of bleeding that are difficult to control.
The activity of the inhibitor is measured by the Bethesda assays or modified Nijmegen Bethesda and is expressed in BU. 1BU neutralizes 50% of the activity of FIX for hemophilia B.
