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Human heparin Cofactor II

Frozen
Packaging options
9-HCII-0190Vial100 µg
9-HCII-0190-1Vial1 mg

Formulation : 50 % Glycerol / H₂O (v/v)

Description of the Human heparin Cofactor II

Activity : 700 to 1 800 units/mg
MW(Da) : 65 600
Extinction coef. : 5.93
Inhibits thrombin, α-chymotrypsin, Cathepsin G, Streptomyces griseus protease B
Isoelectric point : 4.95-5.15
Structure : single chain glycoprotein, 3 potential chains of N-glycosylation, 2 repeated residues of 7 amino acids, reactive site (TVTTVGFMPL-STQVRFTVDR)

Advantages

Supplied lyophilized or frozen.
Expiry date > 1 year.
Glass vial or plastic tubes.
Discount according to quantities.

Informations

The second heparin cofactor is a serine protease inhibitor. It inhibits thrombin, chymotrypsin and other enzymes of the same group. Its rate of inhibition is amplified in the presence of heparin.

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