Plasminogen is the inactive precursor of plasmin, the enzyme responsible for fibrinolysis. plasminogen is synthesized by the liver as a 92 kDa single chain glycoprotein.
Its plasma concentration is approximately 220 µg / mL with a half-life of 2.2 days.
Plasminogen activator transforms it into plasmin.
The level of fibrinogen is a critical factor influencing the rate of fibrinolysis in vivo.
The measurement is based on the use of a monoclonal antibody directed against glu-plasminogen. A second anti-plasminogen monoclonal antibody coupled to peroxidase makes it possible to quantify glu-plasminogen in the sample. (Specialized hemostasis)
- Stability 6 months after opening.
- Reaction time 200 minutes.
- Sensitivity of the assay ranging from 0.06 to 0.5 µg / mL for Glu-Plasminogen.
- Unaffected by the presence of PAP complexes or plasmin obtained from lys-plasminogen.
- 12 x 8-well breakable ELISA strips coated with an anti-plasminogen monoclonal antibody
- 2 adhesives for ELISA plate
- 1 vial x anti-plasminogen monoclonal antibody coupled to peroxidase (POX) 0.3 mL
- 1 vial x 12 mL TMB chromogenic substrate
- 1 bottle x 12 mL stop solution
- 1 vial x washing buffer concentrate 80 mL
- 1 vial x incubation buffer 90 mL
- 1 vial x lyophilized calibrator plasma
