Fibrinogen (Factor I) is a plasma soluble glycoprotein that is synthesized by the liver at a size of 340 kDa and circulating at a concentration of 2.6 to 3 mg/mL.
Fibrinogen is a dimer bound by disulfide bridges composed of 3 pairs of polypeptide chains not identical. Under the action of thrombin, fibrinogen is converted into fibrin. In combination with FXIII, calcium ions, fibrin forms a stable network that ensures coagulation.
Dysibrinogenemic plasma is plasma that has a functional fibrinogen defect.
Most of the patients are asymptomatic, the others may present with moderate hemorrhagic signs but also thromboses.
Special plasmas are derived from patients with a congenital deficiency, severe or moderate, or presenting a particular profile. No buffer or preservatives are added.
Quickly frozen at -80° C, the plasma maintains perfectly intact the matrix.
All plasmas are stable when stored at -40° C to -80° C.
We carefully pack with dry ice during shipment.
No additive or preservative.
Expiry date > 1 year. Plastic vials.
Minimize test time.
Ready to use.
