Tissue factor (FT) is a transmembrane glycoprotein which is primarily responsible for activating coagulation cascades in the event of a vascular breach. The binding of FVII to its receptor, expressed by the cells of the subendothelium exposed by the lesion, allows its very rapid activation by traces of FXa, circulating in trace amounts in vivo. The FT-FVIIa complex then causes the activation of FIX and FX and the formation of thrombin.
All proteins are accompanied by certificates of analysis which describe the appropriate storage conditions. In order for us to guarantee the stability of the product, it is imperative that the storage conditions are observed. Brief centrifugation of the zymogens in their original packaging will fully recover the sample at the bottom of the tube. Never allow protein solutions to stay at room temperature for excessive periods of time. High temperatures can increase the rate of protein degradation. Avoid storing or maintaining diluted protein samples for an extended period of time. In general, purified proteins are inherently more stable in concentrated form. Many proteins are "clingy" by nature. To avoid protein loss due to adsorption, extremely diluted protein samples should be prepared in buffers containing excipients such as bovine serum albumin, polyethylene glycol, Prionex or gelatin.
The vast majority of plasma derivatives is pure (without additives) with > 95 % purity SDS-PAGE. Expiration date of one year from delivery. Delivery in large quantities. Discount according to quantities.
