» Pefakit® APC-R Factor V Leiden Controls

HEMOSTASIS COAGULATION ROUTINE THROMBOPHILIA FACTOR V LEIDEN / APCR

Pefakit® APC-R Factor V Leiden Controls

Control plasmas used to confirm the Factor V Leiden mutation (FV: Q506) in tests to determine the functional phenotype of resistance to activated protein C.

Reference	8-502-21
Presentation	Kit
Format	2 x 3 x 1.0 mL
Quote

Price list, safety data sheets and notices are accessible to our registered customers.

Reference	Presentation	Format	Quote	Product sheet
8-502-21	Kit	2 x 3 x 1.0 mL

Price list, safety data sheets and notices are accessible to our registered customers.

The mutated FV is referred to as FV Leiden. This mutation leads to the replacement at position 506 of an arginine by a glutamine (Arg506Gln), which affects one of the sites of cleavage of FV by PCa. As a result, FV "resists" inactivation by PCa. This factor V loses its function as a cofactor of the protein C system, that is to say of a system which inhibits coagulation; on the other hand, it retains its procoagulant properties. There are other cases of mutations related to the resistance of activated protein C.

The controls are intended for use in conjunction with the Pefakit® APC-R Factor V Leiden (REF 502-01), a functional plasma test to determine resistance to activated protein C caused by the Factor V Leiden mutation (FV: Q506) or equivalent APC stress test.

Results available on different types of analyzers.

- 3 vials of human plasma for negative control.
- 3 flasks of human plasmas for heterozygous control.

Pefakit® APC-R Factor V Leiden

	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION ROUTINE THROMBOPHILIA FACTOR V LEIDEN / APCR