» Phospholipids 0.25 mM

HEMOSTASIS COAGULATION RESEARCH BUFFERS AND SOLUTIONS PHOSPHOLIPIDS

Phospholipids 0.25 mM

Solutions

Mixture of highly purified phospholipids in emulsion.

This mixture of highly purified phospholipids contains synthetic phosphatidyl choline (PC), synthetic phosphstidyl serine (PS) and highly purified sphingomyelin (SM) in Tris-HCl 0.05 mol/L buffer, pH 7.6 at 20°C.
This solution has a long term stabilized phospholipid emulsion with high procoagulant activity.

Application : hemostasis research : procoagulant and anticoagulant pathways.
NAPTT method

Reference	5-PL052
Presentation	Vial
Format	1 x 3.0 mL
Number of assays	30
Quote

Price list, safety data sheets and notices are accessible to our registered customers.

Reference	Presentation	Format	Number of assays	Quote	Product sheet
5-PL052	Vial	1 x 3.0 mL	30

Price list, safety data sheets and notices are accessible to our registered customers.

Phospholipids constitute a catalytic surface for the enzymatic activation of coagulation factors.

Lupus circulating anticoagulants are heterogeneous autoantibodies of the IgG and IgM type directly directed against a variety of anionic phospholipids such as cardiolipin, phosphatidylserine or phosphatidylinositol or against proteins having the capacity to bind to phospholipids such as β2-glycoprotein I (β2 -GPI).

The contribution of phospholipids (PL) does not modify the levels of factors VIII, IX, XI, XII on normal plasmas without deficit nor LA.
The contribution of PL does not modify the levels of factors VIII, IX, XI, XII on the known deficient plasmas with and without LA (isolated constitutional or acquired deficiency)
The supply of PL leads to an increase in factors VIII, IX, XI, XII in plasmas with LA.

This solution can be used in hemostasis tests and for the neutralization of circulating lupus anticoagulants.

Molar concentration :
Phosphatidyl choline: 42% (synthetic)
Phosphatidyl serine : 28% (synthetic)
Sphingomyelin : 30% (egg yolk)

Expiration date of 30 months from the date of manufacture with storage at 2 °C / 8 °C.

For use in all hemostasis tests and neutralization of circulating lupus coagulants. Solution specially designed for the global NAPT method. A coagulation time of approximately 250s is obtained with the phospholipid solution, depending on the instrument used.

For the determination of pro and anticoagulant proteins, this solution is useful for all methods integrating phospholipids such as FII, FVIII, FIX, FX, Proteins C and S..

- 1 glass bottle x 3 mL

	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION RESEARCH BUFFERS AND SOLUTIONS PHOSPHOLIPIDS