HEMOSTASIS COAGULATION ROUTINE REAGENTS FIBRINOLYSIS PLASMINOGEN ACTIVATOR INHIBITOR
TECHNOZYM® PAI-1 Actibind® ELISA Kit
ELISA kit for the antigenic assay of the active form of PAI-1.
The Technozym® PAI-1 Actibind® ELISA kit allows the antigenic detection of the active form of PAI-1 in human plasma in patients with thrombotic disorders (deep vein thrombosis, myocardial infarction), cancers or sepsis.
Informations
Plasminogen activator inhibitor 1 (PAI-1) is a glycoprotein, the primary inhibitor of t-PA and u-PA. It plays an essential role in controlling any excessive activation of fibrinolysis. It is present in plasma associated with vitronectin, in free form or associated with t-PA and in the alpha granules of platelets.
Fibrinolysis corresponds to the solubilization of the fibrinous thrombus by plasmin, an enzyme originating from plasminogen adsorbed to fibrin. Activation of plasminogen takes place by t-PA and u-PA. PAI-1 by inhibiting plasminogen activators, controls the degradation of fibrinous thrombus.
A decrease in fibrinolytic activity promotes the occurrence of thrombosis, while excessive fibrinolysis leads to hemorrhages.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
ELISA Assay
References
| 4-TC16075 | Kit | 12 x 8 tests |
