HEMOSTASIS COAGULATION ROUTINE REAGENTS ACTIVATED FACTOR ASSAYS CHROMOGENIC ASSAYS FACTOR XIA
Rox Factor XIa
Human Factor XIa quantitative assay kit in enriched or highly concentrated preparations of human Factor XIa. Not validated for plasma assays.
The ROX FACTOR XIa is a quantitative enzymatic and chromogenic assay kit for the determination of FXI activity in human FXI concentrates.
Dilution buffer : additional bottles can be ordered under reference 5-1150, specifying the batch number of the box within the limit of available stocks.
Method / Application
The FIXa formed activates FX to factor FXa in the presence of FVIII, thrombin, phospholipids and calcium ions. The amount of FXa generated is determined by hydrolysis of a chromogenic substrate for FXa.
The quantity of para-nitroaniline released during this hydrolysis and measured at 405 nm and is proportional to the concentration of FIXa in the reaction medium. The results are expressed in IU.
The very low presence of FXIa can be measured. (Specialized hemostasis)
Informations
Factor XI (FXI) is a protein synthesized by the liver. It participates in the contact phase which initiates the intrinsic pathway of coagulation.
It is activated by FXIIa to factor FXIa which will itself activate FIX in the presence of calcium ions.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
Colorimetric assay
References
| 5-110050 | Kit | 2 x 50 tests |
