HEMOSTASIS COAGULATION ROUTINE REAGENTS ACTIVATED FACTOR ASSAYS CHROMOGENIC ASSAYS FACTOR IXA
HEMOSTASIS COAGULATION ROUTINE REAGENTS LYOPHILIZED CALIBRATORS AND CONTROLS SPECIALTY CONTROLS
Factor IXa Control
Purified preparation of Factor IXa for the ROX FIX-A kit, titrated against the international standard WHO.
Quality control plasma for the determination of FIXa in colorimetry.
Method / Application
The ROX FIX-A is a chromogenic enzymatic assay kit for the determination of very small amounts of FIXa in human FIX concentrates.
The results are expressed in IU. The sensitivity of the assay is 0.1 mIU / mL. This method is based on the activation of FX by FIXa (considered a contaminant in FIX concentrate) in the presence of FVIII, thrombin, phospholipids and calcium ions.
The amount of FXa generated is determined by hydrolysis of a chromogenic substrate for FXa. The quantity of para-nitroaniline released during this hydrolysis and measured at 405 nm is proportional to the concentration of FIXa in the reaction medium.
Informations
FIX is a vitamin K dependent glycoprotein synthesized by the liver.
FIX can be activated to FIX in FIXa by FXIa or by FVIIa in the presence of phospholipids and calcium.
A person who is deficient in FIX has hemophilia B.
Documentation
Download the product sheetPrice list, safety data sheets and notices are accessible to our registered customers.
Colorimetric assay
References
| 5-9588 | Vial | 10 x 2.0 mL |
