Recombinant tissue Factor pathway inhibitor (TFPI)

 
Formulation : Sterile filtered colorless solution (1mg/ml) in 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea, 10% glycerol.

Inhibits the FVIIa and tissue Factor in the complexe Xa/TFPI/FVIIa/TF
MW(Da) : 34 300



Informations

TFPI is an anticoagulant protein produced by the endothelial cell and found on its surface. Its role is to inhibit the early phases of coagulation by blocking the FT-FVIIa complex as well as the Fxa.

Tissue Factor Pathway Inhibitor (TFPI) produced in E.coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (29-304) and having a molecular mass of 34.3kDa.
TFPI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.


Documentation

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References

6-H7035-P01Vial5 µg
6-H7035-P01-50Vial50 µg