Previously called antithrombin III (abbreviated ATIII), human antithrombin is one of the major physiological inhibitors of coagulation. A natural serine protease inhibitor, antithrombin acts mainly on thrombin (IIa) and activated Factor X (FXa), as well as on activated forms of factors IX, XI and XII. This reaction is catalyzed by heparin. The normal level of antithrombin is between 80 and 120% in adults and it is about half in newborns. Antithrombin deficiency predisposes to thrombosis.
Special plasmas are derived from patients with a congenital deficiency, severe or moderate, or presenting a particular profile. No buffer or preservatives are added. Quickly frozen at -80° C, the plasma maintains perfectly intact the matrix. All plasmas are stable when stored at -40° C to -80° C. We carefully pack with dry ice during shipment. No additive or preservative. Expiry date > 1 year. Plastic vials.
Minimize test time. Ready to use.
