Factor XII (FXII) is a glycoprotein synthesized by the liver. FXII participates in the contact phase which initiates the intrinsic pathway of coagulation. Activated on contact with a negatively charged surface, it becomes capable of activating prekallikrein and kallikrein (amplified by KHPM) then FXI to FXIa in the presence of KHPM. The FXIa thus formed activates the FXII in FXIIa, amplifying the reaction.
Special plasmas are derived from patients with acquired deficiency, severe or moderate, or presenting a particular profile. No buffer or preservatives are added. Quickly frozen at -80° C, the plasma maintains perfectly intact the matrix. All plasmas are stable when stored at -40° C to -80° C. We carefully pack with dry ice during shipment. No additive or preservative. Expiry date > 1 year. Plastic vials.
Minimize test time.
Ready to use.
