HEMOSTASIS COAGULATION RESEARCH REAGENTS COFACTORS FACTOR VA
 
 

Human Factor Va

 

Origin : Human Blood / Plasma
Formulation : 50 % Glycerol / 5 mM CaCl₂ (v/v)
Structure: 2 sub-units; heavy chain (94kDa) and light chain (74 kda)

1 900 to 4 600 units/mg
MW(Da) : 168 000
Coefficient d'extinction : 17.4
Determination of activity: coagulation test
 


Advantages

The vast majority of coFactors is pure (without additives) with > 95 % purity SDS-PAGE.
Expiration date of one year from delivery.
Delivery in large quantities.
Discount according to quantities.


Informations

A cofactor is a chemical substance, which binds to a protein, and which is necessary for the biological activity of the latter.
These proteins are often enzymes, and cofactors can be thought of as "helper molecules" aiding in biochemical transformations.
Factor V (FV) is a protein mainly synthesized by the liver. It is the enzymatic cofactor of FX and is activated in FVa by thrombin and / or FXa.
It forms with FXa a complex which, in the presence of phospholipids and calcium, activates prothrombin to thrombin.
The FVa is neutralized by the PCa.


Documentation

Download the product sheet
Price list, safety data sheets and notices are accessible to our registered customers.


 
 
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References

9-HCVA-0110Vial50 µg
9-HCVA-0110-1Vial1 mg

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