Factor V (FV) is a protein mainly synthesized by the liver. It is the enzymatic cofactor of FX and is activated in FVa by thrombin and / or FXa.
It forms with FXa a complex which, in the presence of phospholipids and calcium, activates prothrombin to thrombin. The FVa is neutralized by the PCa.
- Deficient plasma of human origin, stabilized and lyophilized with an activity < 3% of the corresponding coagulation factor.
- All other coagulation factors have normal values.
- Deficient plasma obtained by immunoadsorption.
- The FV-deficient plasma is used for the determination of FV by the one-step method using a specific thromboplastin. It can be used for the determination of resistance to PCa.
- Deficient plasma can be aliquoted and frozen for 1 month at -20 °C after reconstitution.
- 5 vials x 1 mL lyophilized plasma