Factor II or prothrombin, is the precursor protein of thrombin, a key enzyme in coagulation.
Prothrombin is synthesized by the liver and is dependent on vitamin K.
FII is activated to thrombin by the prothrombinase complex. Its half-life is 50 to 120 hours.
- Deficient plasma of human origin, stabilized and lyophilized with an activity <1% of the corresponding coagulation factor.
- All other coagulation factors have normal values.
- Deficient plasma obtained by immunoadsorption.
- The plasma deficient in FII is used for the determination of FII by the one-step method based on the prothrombin time.
- Deficient plasma can be aliquoted and frozen for 1 month at -20 °C after reconstitution.
- 5 vials x 1 mL lyophilized plasma