ADAMTS-13 is an enzyme responsible for the cleavage of von Willebrand factor under blood flow conditions.
A functional defect in the activity of this enzyme leads to the presence of high molecular weight isoforms of vWF, and thus leads to increased platelet aggregation mainly in areas of microvascularization.
This is the known major cause of Thrombotic Thrombocytopenic Purpura (TTP).
- Stability 6 months after opening.
- Reaction time 210 minutes.
- 5 calibrators from 0 to 1 IU / mL (depending on the lot).
- 2 controls from 0.20 to 0.70 IU / mL (depending on the lot).
Since October 2015, the controls and calibrators in the kit have been calibrated against the 1st WHO international standard (NIBSC code 12/252) in IU / mL.
- 12 x 8 wells breakable ELISA test strips
- 2 adhesives for ELISA plate
- 1 vial x conjugated antibody (0.3 mL)
- 1 vial x chromogenic substrate (12 mL)
- 1 vial x stop solution (12 mL)
- 1 vial x 10 x wash buffer concentrate (80 mL)
- 1 vial x incubation buffer (90 mL)
- 5 vials x lyophilized calibrators (0.5 mL)
- 1 vial x lyophilized high control plasma (0.5 mL)
- 1 vial x lyophilized low control plasma (0.5 mL)