» RVV-Facteur V Activator

HEMOSTASIS COAGULATION RESEARCH VENOM PROTEASES VIPERA RUSSELII VENOM

RVV-Facteur V Activator

Product derived from the venom of Vipera russelli in lyophilized form.

MW (Da) : 28 000
RVV-V is a specific activator of FV to FVa from Russell's viper venom which converts single chain FV into an active 2 chain compound. Activated FV is not stable and loses activity within 20 hours at 37 ° C.
Therefore, RVV-V is also used to selectively inactivate FV in plasma in order to prepare a routine reagent for determination of FV.

Reference	8-121-03
Presentation	Vial
Format	1 x 1000 U
Quote

Price list, safety data sheets and notices are accessible to our registered customers.

Reference	Presentation	Format	Quote	Product sheet
8-121-03	Vial	1 x 1000 U

Price list, safety data sheets and notices are accessible to our registered customers.

Snake venom proteases are interesting tools for studying coagulation reactions. Venoms contain more than 20 different compounds, mainly proteins and polypeptides. Some snake venoms have very specific effects on various biological functions, including blood clotting, regulation of blood pressure, transmission of nerve or muscle impulses.
They were developed for use as diagnostic tools. Plasma coagulation factors are usually inactive and require proteolytic activation as a first step towards a chronometric or colorimetric assay. It is often advantageous to use specific enzymes from snake venoms to activate coagulation factors rather than using physiological activators. In contrast to other activators, many snake venom enzymes are not dependent on cofactors, phospholipids, or calcium ions.

The isolated snake venom proteins can be used in coagulation and platelet aggregation tests, in photometric tests as well as in immunological systems.

Venom proteases are obtained from highly purified homogeneous preparations with indication of the activities.

Daboia Russelii venom (lyophilized)
Daboia Russelii venom (frozen)

	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION RESEARCH VENOM PROTEASES VIPERA RUSSELII VENOM