TFPI is an anticoagulant protein produced by the endothelial cell and found on its surface. Its role is to inhibit the early phases of coagulation by blocking the FT-FVIIa complex as well as the Fxa.
Tissue Factor Pathway Inhibitor (TFPI) produced in E.coli is a single, non-glycosylated polypeptide chain containing 299 amino acids (29-304) and having a molecular mass of 34.3kDa.
TFPI is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
We offer a selection of inhibitors derived from benzamidine. They can help in the characterization of trypsin-like enzymes. Most inhibitors exhibit a selective inhibitory activity on certain trypsin-like proteinases of physiological relevance. However, each inhibitor will of course display a characteristic action on others serines proteinases.
Store at +2°C/+8°C if entire vial will be used within 2-4 weeks.
Store, frozen at -25°C/-15°C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Purity > 85.0% as determined by SDS-PAGE.
Avoid multiple freeze-thaw cycles.
