» Human antithrombin

HEMOSTASIS COAGULATION RESEARCH INHIBITORS NATURAL PROTEASE INHIBITORS

Human antithrombin

Formulation : 50/50 (v/v) glycerol/H₂O

Inactivates several serine proteinases
Activity : 0.7 to 1.0 mole thrombin / mole AT
MW(Da) : 58 000
Extinction coef. : 14.5
Isoelectric point: 4.9-5.3
Structure: single chain, 3 intrachain disulfide bonds, 10% alpha-helise, 30-40% structure-beta, 50% random coil, scissile bond (Arg 385-Ser 386)

Reference	9-HCATIII-0120
Presentation	Vial
Format	1 mg
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Price list, safety data sheets and notices are accessible to our registered customers.

Reference	Presentation	Format	Quote	Product sheet
9-HCATIII-0120	Vial	1 mg

Price list, safety data sheets and notices are accessible to our registered customers.

Antithrombin is a glycoprotein of the serpin family, synthesized by the liver with a half-life of 3 days. It is the most potent of the physiological inhibitors of coagulation. It mainly inhibits thrombin but also at a lower level FIXa, FXa, FXIa. Its inhibitory action is amplified in the presence of heparin or heparan sulfate.

Most inhibitors exhibit a selective inhibitory activity on certain trypsin-like proteinases of physiological relevance. However, each inhibitor will of course display a characteristic action on others serines proteinases.

Supplied lyophilized or frozen.
Expiry date > 1 year.
Glass vial or plastic tubes.
Discount according to quantities.

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	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION RESEARCH INHIBITORS NATURAL PROTEASE INHIBITORS