Plasminogen activator inhibitor (PAI-1) is a glycoprotein, the main inhibitor of t-PA and u-PA. It plays an important role in controlling excessive fibrinolysis. PAI-1 is mainly synthesized by vascular endothelial cells, as well as by other cells (hepatocyte, SMC, fibroblasts...). It circulates in plasma in 3 forms: an active form bound to vitronectin, a latent free form and an inactive form. By inhibiting t-PA and u-PA, PAI-1 limits plasminogen activation and controls fibrinous thrombus degradation.
Packaging in plastic cryotubes or in bottles of at least 100 mL.
Frozen, immuno-depleted plasmas are certified to have less than 1% for the deficient factor considered, both for the antigenic and functional assay in haemostasis.
This box is intended for research use
- No bovine additives
- No reconstitution error
- No deterioration of plasmas linked to freeze-drying
- Cryotubes ready to use after thawing (4 min at 37°C).
- 10 cryotubes x 1 mL or 100 mL vial of frozen plasma.