Factor VIII is a glycoprotein mainly synthesized by the liver.
It circulates in the plasma in the form bound to VWF which protects it from rapid proteolytic degradation.
It is activated by FXa or thrombin in FVIIIa which will complex with FIXa in the presence of phospholipids to activate FX in FXa.
A patient who is deficient in FVIII has hemophilia A.
Special plasmas are derived from patients with a congenital deficiency, severe or moderate, or presenting a particular profile.
No buffer or preservatives are added.
Quickly frozen at -80° C, the plasma maintains perfectly intact the matrix.
All plasmas are stable when stored at -40° C to -80° C.
We carefully pack with dry ice during shipment.
No additive or preservative.
Expiry date > 1 year.
Minimize test time.
Ready to use.