Plasminogen activator inhibitor (PAI-1) is a glycoprotein, the primary inhibitor of t-PA and u-PA. It plays an important role in controlling excessive fibrinolysis.
PAI-1 is mainly synthesized by vascular endothelial cells, as well as by other cells (hepatocyte, CML, fibroblasts, etc.). It circulates in plasma in 3 forms: an active form linked to vitronectin, a latent free form and an inactive form. By inhibiting t-PA and u-PA, PAI-1 limits the activation of plasminogen and controls the degradation of the fibrinous thrombus.
- Plasmas verified negative for all tests required by the FDA.
- Packaging in plastic cryotubes suitable for all STA-R type micro-cup supports.
- The frozen, immuno-depleted plasmas are certified to have less than 1% for the deficient factor considered, both for the antigenic assay and for functional hemostasis.
- No bovine additives.
- No reconstitution error.
- No deterioration of plasmas linked to freeze-drying Ready to use after thawing (4 min at 37 °C).
- 10 cryotubes x 1 mL of frozen plasma
