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Human plasma immuno-depleted in t-PA and buffered with 20mM HEPES
Tissue plasminogen activator (t-PA) is a serine esterase that plays a key role in the fibrinolysis system. It is present in plasma, 95% bound to PAI-1, in platelets and in some tissues.
In plasma, the enzymatic activity of t-PA on plasminogen is very low, it is amplified 200 to 400 times when t-PA and plasminogen are adsorbed to fibrin.
The frozen, immuno-depleted plasmas are certified to have less than 1% for the deficient factor considered, both for the antigenic assay and for functional hemostasis.
Cryopep Thrombosis Haemostasis Catalogue 2021
Cryopep Haemostasis Research Catalogue 2021