Rat mAb anti-mouse protein C & protein C activated
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These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
These kits are intended for in vitro diagnostic use.
These kits are for research use only and are not intended to be used for diagnostic procedures.
Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
Biological risk products.
Storage between 2 and 8 ° C.
Reactive in liquid form.
Reactive in lyophilized form.
Reactive in frozen form.
Stability after opening at 2-8 ° C.
Products that can be refrozen.
Stability 12 months after refreezing at -20 ° C.
Antigen : mouse PC and aPC
Application : Western Blot (PC only), ELISA Host : Rat Immunogen : Purified Mouse Protein C
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The Safety Data Sheets and Notices are accessible to our registered customers.
Protein C (PC) is a vitamin K dependent plasma protein that regulates coagulation by inhibiting FVa and FVIIIa and helps limit the extension of the thrombus. Numerous clinical studies have shown that a PC deficiency (acquired or congenital) is a risk factor for venous thrombosis. PC is a 62 kDa glycoprotein, synthesized by the liver in the presence of vitamin K. PC circulates in plasma in an inactive form, at a concentration of approximately 4 μg/mL. Thrombin bound to thrombomodulin loses its procoagulant properties and activates PC into activated PC. PCa in the presence of its cofactor, protein S, calcium and phospholipids, is capable of to inactivate the FVa and FVIIIa, true catalysts of coagulation, thus blocking the amplification loop of thrombin generation and limiting the extension of the thrombus.
The vast majority of antibodies is pure (without additives) with > 95 % purity SDS-PAGE. Stock antidobies are supplied in 50 % glycerol/water (v/v) for ease of storage and use. Both small, laboratory scale and bulk, production scale quantities are available. Expiration date of one year from delivery.
Custom needs by supplying you conjugated with biotin, HRP, FITC or other conjugates. Special formulations are available upon request. Discount according to quantities