The pNAPEP® Chromogenic Peptide Substrates line is a range of high-quality substrates for testing protease serines.
They target enzymes involved in coagulation and fibrinolysis such as thrombin, Factor Xa, Factor XIIa, kallicrein, activated C protein, plasmin and plasminogen-SK.
Some of our pNAPEP chromogenic substrates are equivalent to those of the brand CHROMOGENIX, WERFEN, PENTAPHARM DSM or DIAGNOSTICA STAGO. Examples include chromogenic substrates S-2238, S-2765, S-2732, S-2403, S-2444, S-2366, S-2251, S-2288, S-2403, S-2302, Pefachrom TH, Pefachrom VIIa, Pefachrom IXa and CBS 3139. These are synthetic peptides that react with proteolytic enzymes by releasing a colour that can be followed by spectrophotometry and whose intensity is proportional to the proteolytic activity of the enzyme. Typically, such chromogenic substrates are composed of 3 to 5 natural or artificial amino acids. Their structures can be protected in N-terminal to reduce undesirable degradation by aminopeptidases.
Their C-terminal ends are modified so that, during the cleavage of the amide bond, a chromogenic group is released. The most commonly used group is p-nitroaniline (pNA), which absorbs light at a wavelength of 405 nm.
Records and certificates of analysis provided.
Safety Data Sheets (SDS) provided.
Prolonged stability after reconstitution (> 3 months).
We can provide milligram per gram.
Discount applicable according to quantities
