» CRYOcheck™ APCR Positive Control

HEMOSTASIS COAGULATION ROUTINE THROMBOPHILIA FACTOR V LEIDEN / APCR

CRYOcheck™ APCR Positive Control

Chronometric assay

Heterozygous control for the validation of the assay of resistance to protein C activated by the coagulant method in hemostasis.

Quality control plasmas are collected from a donor confirmed heterozygous for the Factor V Leiden mutation by molecular biology and not having anticoagulant therapy.

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Reference	APCR-05
Presentation	Kit
Format	25 x 0.5 mL
Quote

Price list, safety data sheets and notices are accessible to our registered customers.

Reference	Presentation	Format	Quote	Product sheet
APCR-05	Kit	25 x 0.5 mL

Price list, safety data sheets and notices are accessible to our registered customers.

Resistance to activated protein C (RPCa) is an anomaly described by Dahlbäck in 1993.
Bertina discovered in 1994 the presence of a mutation in the factor V (FV) gene.
This mutation leads to the replacement at position 506 of an arginine by a glutamine (Arg506Gln), which affects one of the sites of cleavage of FV by PCa.
As a result, FV "resists" inactivation by PCa. The mutated FV is referred to as FV Leiden. This factor V loses its function as a cofactor of the protein C system, that is to say of a system which inhibits coagulation; on the other hand, it retains its procoagulant properties. There are other cases of mutations related to the resistance of activated protein C.

- Plasmas verified negative for all tests required by the FDA
- Expiration date of 3 years from the date of manufacture with storage between -40 ° C and -80 ° C
- Defrost in 3 min at 37 ° C
- Ready to use
- Packaging in plastic cryotubes suitable for all STA-R type microgodets

- 25 cryotubes x 0.5 mL of frozen plasma

	These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
	These kits are intended for in vitro diagnostic use.
	These kits are for research use only and are not intended to be used for diagnostic procedures.
	Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
	Biological risk products.
	Storage between 2 and 8 ° C.
	Reactive in liquid form.
	Reactive in lyophilized form.
	Reactive in frozen form.
	Stability after opening at 2-8 ° C.
	Products that can be refrozen.
	Stability 12 months after refreezing at -20 ° C.
	Manufacturer.
	Importer
	Distributor.

HEMOSTASIS COAGULATION ROUTINE THROMBOPHILIA FACTOR V LEIDEN / APCR