VIPERA RUSSELII VENOM

Cat Num.ProductMW(Da)ConservationtargetSize
9-RVVV-2000

RVV-V

28 000-25° C / -15° CRVV-V is a specific factor V activator from Russell’s viper venom converts single chain factor V to an active two chain form. Activated factor V is not stable and loses its activity within 20 hours at 37° C. Therefore, RVV-V is used to destabilize and selectively inactivate factor V in plasma and thus to prepare a routine reagent for the factor V determination.100 µg
8-121-03

RVV-V

28 0002° C / 8° CRVV-V is a specific factor V activator from Russell’s viper venom converts single chain factor V to an active two chain form. Activated factor V is not stable and loses its activity within 20 hours at 37° C. Therefore, RVV-V is used to destabilize and selectively inactivate factor V in plasma and thus to prepare a routine reagent for the factor V determination.1 000 U

Description


Snake venom proteases are useful tools for studying coagulation reactions.
Venoms contain more than 20 different compounds, mostly proteins and polypeptides.
Some of the proteins in snake venom have very specific effects on various biological functions including blood coagulation, blood pressure regulation, transmission of the nervous or muscular impulse and have been developed for use as diagnostic tools.
Plasma coagulation factors are usually inactive and require proteolytic activation as a first step towards a chronometric or colorimetric assay.
It is often advantageous to use specific enzymes from snake venoms to activate coagulation factors rather than physiological activators.
In contrast to other activators, many snake venom enzymes are not dependent from cofactors, phospholipid or calcium ions.

Characteristics


All of our venom products are supplied in 50 % glycerol / water for storage at -20° C or supplied lyophilized at 2-8° C.
Expiry date = 1 year

Advantages


The venom proteases offered are highly purified, homogenous preparations with the indicated activities.

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