TECHNOZYM® T-PA-PAI-1 COMPLEX ELISA
||Conditioning||Package size ||
|4-TC12080||kit||12 x 8 ||
ELISA kit used for determination of t-PA-PAI-1 complexes in plasma.
The t-PA-PAI-1 complex ELISA is useful for the detection of elevated amounts of t-PA-PAI-1 complex in patients with liver disease.The t-PA-PAI-1 test is a solid phase enzyme immunoassay. This test system measures t-PA-PAI-1 complexes only. Free t-PA or PAI-1 are not measured nor are other complexes which include these molecule detected. The test measures from 0 ng/ml- 20 ng/ml. The inter- and intraassay variations are less than 10 % and 0 %, respectively.
- 1 vial of calibrator, complex t-PA-PAI-1
- 1 vial of Conjugate
- 1 bottle of Diluent (20 mL)
- 1 bottle of Conjugate Dilution buffer (12 mL)
- 1 bottle of TMB (12 mL)
- 1 bottle of Stop Solution (15 mL)
- 1 bottle of Wash Solution, concentrate (20 mL)
- 12 ELISA test strips (12 x 8 wells)
Tissue plasminogen activator (t-PA) and urokinase are the agents that convert plasminogen to the active plasmin, thus allowing fibrinolysis to occur. t-PA is released into the blood very slowly by the damaged endothelium of the blood vessels, such that, after several days (when the bleeding has stopped), the clot is broken down. This occurs because plasminogen became entrapped within the clot when it formed; as it is slowly activated, it breaks down the fibrin mesh.