TECHNOZYM® ADAMTS-13 INH CONTROL SET
|4-5450463||2 x 0,5 mL ||
Control plasma set for TECHNOZYM® ADAMTS-13 INH.
Positive and negative control plasma; lyophilised; 1 vial each; 0.5 mL. Concentrations are lot-specific; consult the label on the vial.
Most of anti-ADAMTS-13 autoantibodies inhibit ADAMTS-13 activity and thus non-cleaved ULvWF accumulates in plasma. This is believed to be the major cause for thrombotic thrombocytopenic purpura (TTP). TECHNOZYM® ADAMTS-13 INH test makes it possible to differentiate between congenital (gene polymorphisms) and acquired (autoantibodies) TTP when coupled to an activity assay and to control efficacy of plasma exchange therapy.