TECHNOZYM® ADAMTS-13 CALIBRATOR SET
|4-5450561||6 x 0,5 mL ||
Calibrator plasma set for TECHNOZYM® ADAMTS-13 ELISA kit.
Calibrators (Standards) are numbered from 1 to 6; lyophilised; 1 vial each; 0.5 mL. Concentrations are lot-specific; consult the label on the vial or the batch table.
ADAMTS-13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) is an enzyme (vWF-cleaving protease or vWF-CP) that specifically cleaves unusually large von Willebrand factor (vWF) multimers, which induce platelet thrombus formation under high shear stress. If the activity of ADAMTS13 is lowered for some reason, however, unusually large vWF multimers may accumulate within blood causing thrombosis due to platelet aggregation, which in turn may lead to TTP (thrombotic thrombocytopenic purpura).