FLETCHER TRAIT PLASMA
||Conditioning||Package size ||
|4-5205006||2 x 1,0 mL||40 ||
Lyophilized and stabilized human pre-kallikrein deficient plasma for diagnosing pre-kallikrein deficiency.
A deficiency in pre-kallikrein will prolong the activated partial thromboplastin time (aPTT) considerably but does not usually result in the expected haemorrhagic tendency. This abnormality in the activating phase of the aPTT can be corrected in vitro by adding Factor XII Deficient Plasma or Fitzgerald Trait Plasma (HMW-Kininogen Deficient Plasma). In addition a prekallikrein deficiency will also affect fibrinolysis, kinin formation and the complement system.
Factors of the intrinsic Pathway are tested with activated Partial Thromboplastin Time (aPTT) reagents using plasma deficient of Factor VIII, IX, XI and XII as well as Fitzgerald and Fletcher Trait Plasma.
Deficient Plasmas are lyophilised from human plasma
All other coagulation factors are in the normal range.
All deﬁcient plasma have been obtained from patients with congenital deficiencies.