FITZGERALD TRAIT PLASMA
||Conditioning||Package size ||
|4-5204006||2 x 1,0 mL||40 ||
Immune-adsorbed lyophilized and stabilized human high molecular weight kininogen deficient plasma.
HMW-kininogen deficient plasma show a prolonged coagulation time in the aPTT test. This abnormality is not accompanied by the expected haemorrhagic tendency. The aPTT abnormality can be neutralised in vitro by the addition of factor XII deficient plasma or Fletcher Trait Plasma (prekallikrein deficient plasma). In addition on the effect on the aPTT test, Fitzgerald Trait Plasma also shows abnormalities in fibrinolytic activity, the formation of kinins and the permeability of the vascular wall.
Factors of the extrinsic and Common Pathway are tested with Prothrombin Time (PT) reagents using plasma deficient of Factor II, V, VII and X
Deficient Plasmas are lyophilised from human plasma.
All other coagulation factors are in the normal range.
All deﬁcient plasma have been obtained by immunadsorption.