FIX is a vitamin K dependent glycoprotein synthesized by the liver.
The FIX can be activated in FIX in FIXa by the FXIa or by FVIIa in the presence of phospholipids and calcium.
A person who is deficient in FIX has hemophilia B.
The CRYOcheck™ Chromogenic Factor IX is used to identify FIX deficiency and helps in the management of hemophilia B in people aged 2 years and older
- Intended to be used on automated coagulation analyzers (protocols available on request)
- Linearity: 0-200%
- Stable 24h on analyzers
- Reagents refreezable 30 days at -70° C
- Convenient frozen format - ready to use in minutes, with no risk of reconstitution error
- Thawed reagents stable for 48 hours in original vials when stored at 2-8°C
- Reagents can be re-frozen at -70°C for up to one month limiting reagent loss
- Excellent accuracy at low FIX activity
- 4 vials of reagent 1 (human FVIII, human FX, bovine FV) (0.75 mL)
- 4 vials of reagent 2 (human FXIa, human FII) (2.3 mL)
- 4 vials of reagent 3 (FXa substrate) (1.0 mL)
- 4 vials of Tris-BSA dilution buffer (10.0 mL)
