These kits are manufactured in accordance with the 98/79 EC directive for in vitro diagnostic devices. Only CE marked products can be used for diagnostic applications in Europe.
These kits are intended for in vitro diagnostic use.
These kits are for research use only and are not intended to be used for diagnostic procedures.
Federal Drug Administration, FDA validates diagnostic kits for in vitro diagnostic use in the United States.
Biological risk products.
Storage between 2 and 8 ° C.
Reactive in liquid form.
Reactive in lyophilized form.
Reactive in frozen form.
Stability after opening at 2-8 ° C.
Products that can be refrozen.
Stability 12 months after refreezing at -20 ° C.
Manufacturer.
Importer
Distributor.
Determination of ADAMTS-13 activity in colorimetry
TECHNOZYM® ADAMTS-13 Activity ELISA is a chromogenic test for the determination of ADAMTS-13 activity in human plasma by ELISA method at 450nm.
ADAMTS13 (a disintegrin-like and metalloproteinase with thrombospondin type 1 motif 13) is an enzyme (VWFcleaving protease or VWF-CP) that specifically cleaves von Willebrand factor (VWF), which induce platelet thrombus formation under high shear stress.
If the activity of ADAMTS13 is lowered for some reason, however, unusually large VWF multimers may accumulate, causing thrombosis due to platelet aggregation, which in turn may lead to TMA (thrombotic microangiopathy) such as TTP (thrombotic thrombocytopenic purpura).
- Stability 6 weeks after opening a set.
- Reaction time 190 minutes.
- 6 calibrators from 0 to 1 IU / mL. (depending on the lots)
- 2 controls of 0.20 to 0.70 IU / mL. (depending on the lots)
Since October 2015, the controls and calibrators in the kit have been calibrated against the 1st WHO international standard (NIBSC code 12/252) in IU / mL.
- 12 x 8 wells ELISA test stripes
- 3 adhesives for ELISA plate
- 2 vials x lyophilized substrate (6 mL)
- 1 vial x conjugated antibody (12 mL)
- 1 vial x chromogenic substrate (12 mL)
- 1 bottle x stop solution (12 mL)
- 1 vial x reaction buffer (30 mL)
- 1 vial x Wash Buffer Concentrate 10 x (53 mL)
- Sample dilution microplate
- 6 vials x lyophilized calibrators (0,5 mL)
- 1 vial x lyophilized low control plasma (0,5 mL)
- 1 vial x lyophilized high control plasma (0,5 mL)
