Factor XII (FXII) is a glycoprotein synthesized by the liver. FXII participates in the contact phase which initiates the intrinsic pathway of coagulation. Activated on contact with a negatively charged surface, it becomes capable of activating prekallikrein and kallikrein (amplified by KHPM) then FXI to FXIa in the presence of KHPM. The FXIa thus formed activates the FXII in FXIIa, amplifying the reaction.
The vast majority of antibodies is pure (without additives) with > 95 % purity SDS-PAGE. Stock antidobies are supplied in 50 % glycerol/water (v/v) for ease of storage and use. Both small, laboratory scale and bulk, production scale quantities are available. Expiration date of one year from delivery.
Custom needs by supplying you antibodies conjugated with biotin, HRP, FITC or other conjugates. Special formulations are available upon request. Discount according to quantities
