Factor VIII is a glycoprotein mainly synthesized by the liver. It circulates in the plasma in the form bound to VWF which protects it from rapid proteolytic degradation. It is activated by FXa or thrombin in FVIIIa which will complex with FIXa in the presence of phospholipids to activate FX in FXa. A patient who is deficient in FVIII has hemophilia A.
The vast majority of antibodies is pure (without additives) with > 95 % purity SDS-PAGE. Stock antidobies are supplied in 50 % glycerol/water (v/v) for ease of storage and use. Both small, laboratory scale and bulk, production scale quantities are available. Expiration date of one year from delivery.
Custom needs by supplying you conjugated with biotin, HRP, FITC or other conjugates. Special formulations are available upon request. Discount according to quantities